In this second adaptation of the Fleming novels… Bond is sent to New York City to investigate "Mr. Big", an agent of SMERSH and a criminal voodoo leader. With no time for superstition—and with the help of his colleague in the CIA, Felix Leiter, Bond tracks "Mr. Big" through the jazz joints of Harlem, to the everglades and on to the Caribbean, knowing that this criminal heavy hitter is a real threat. No-one, not even the mysterious Solitaire, can be sure how their battle of wills is going to end…

Ian Fleming's literary debut of British Secret Service agent 007 is stylishly adapted to the sequential art medium by Van Jensen and Matt Southworth in the official James Bond: Casino Royale graphic novel. Sent to a French casino in Royale-les-Eaux, Bond aims to eliminate the threat of the deadly Le Chiffre by bankrupting the ruthless SMERSH operative at the baccarat table. However, when the luck of the draw favors his enemy, 007 becomes the target of assassins and torturers in a high-stakes game of cat-and-mouse.